[4] In 1722, he inoculated three of the children of the Prince and Princess of Wales against smallpox, following the introduction of the process into the country from Turkey by Lady Mary Wortley Montagu.
[2] At St George's Hospital, on 6 December 1735, he performed the first recorded successful appendicectomy (which is the surgical removal of the vermiform appendix).
[5] The patient was an 11-year boy named Hanvil Anderson who had an inguinal hernia combined with an acutely inflamed appendix.
[3] It was only careful research by John Blair Deaver in the early twentieth century that restored to Amyand the credit he deserved.
[5] As biographer P. G. Creese put it: "Claudius Amyand was not a man of genius, but one of solid worth who merits a nod of recognition from medical history, too long denied to him.