Clay Junior-Senior High School is a public high school in Clay Township, Ohio, United States, located four miles (6 km) north of the Portsmouth in Scioto County.

Clay is a rural high school serving about 300 students in grades 7–12 in Southern Ohio.

After new Ohio legislation allowing the district to proceed, a bond issue was placed on the March 2008 ballot to build a new preK-12 facility.

With a bond issue to raise $325,000 (along with matching funds from the state and federal government for a total cost of nearly $600,000) a new high school building, which opened its doors on February 1, 1956, was built on Clay High Street.

Additional upgrades and renovations have occurred to all three buildings over the years including improvements to the high school gym, new science laboratories, renovations to all the restroom facilities, new roofs, and air conditioning for all three buildings.

The building and grounds are located on Clay High Street just off U.S. Route 23 and Lochner Road in Rosemount, which is nestled in a rural, community area of apartments, small businesses, homes, and farmland.

The campus consists of several acres in which PK-12 building and several athletic fields (baseball and soccer) are located.

The old Clay Jr.-Sr. High School building was shaped somewhat as an "E" (facing east) from an aerial view.

The school has new tennis courts (as of 2019) located on Rose Valley Road behind where the old Rosemount Elementary stood.

The latest Ohio Department of Education report card indicated CHS met the graduation, AYP (average yearly progress), and attendance percentages/rates.

The school currently meets on a 47-minute, eight-period schedule in which students attend each class daily.

These academic opportunities include, but are not limited to, AP courses, Art I-IV, band, Chemistry I & II, chorus, computer applications, pre-engineering courses, economics, industrial arts, physics, senior composition, Spanish I-IV, and web page design.

Clay's graduating classes, which average about 35 students, have received in excess of $300,000 each year in scholarship money.

[22][23] The team was 79–1 in those three years under the direction of Carol Vice, a member of the Clay Coaches' Hall of Fame.

[23] The boys' basketball team made it to the OHSAA Final Four in 1969 under the direction of Arch Justus, who is also a member of the Clay Coaches' Hall of Fame[24] and the Ohio Basketball Coaches Hall of Fame.

Terri Boldman, a member of the Clay Coaches' Hall of Fame[24] and current high school assistant principal, guided the girls to the OHSAA Final Four.

[25] Words to the school fight song were written by Wanda Lake, a Clay alumna.

[35] The song's lyrics are sung to the tune of the trio section from the popular march, Military Escort, by Harold Bennett, a pseudonym of Cincinnati composer and bandmaster Henry Fillmore (1881-1956).