Clayton Lake is an unincorporated village in Aroostook County, Maine, United States.

[6] Mail for Clayton Lake was serviced by the post office in Portland, who sent the mail via truck to Boston, then by plane to Montreal and then by train to Lac de la Frontiere, Quebec, before being delivered to Clayton Lake.

The lake contains several species of fish, including landlocked salmon, brook trout and rainbow smelt.

[7] Clayton Lake is only accessible via private roads within the North Maine Woods.

There is a private turf landing strip located north of Clayton Lake.