During his collegiate career for the East Carolina Pirates, he batted .272 with 11 home runs and 82 runs batted in (RBIs) and earned second team All-Colonial Athletic Association honors in his junior year, as well as making a couple of All-Regional teams in three appearances in the NCAA baseball tournament.

[2] The Cleveland Indians selected McCullough in the 22nd round of the 2002 Major League Baseball draft.

[1] After one season as a volunteer assistant coach for East Carolina,[2] McCullough served as a manager in Minor League Baseball for the Toronto Blue Jays organization from 2007 to 2014, working in the Rookie and Single–A levels and compiling a record of 629–559.

[3] before being hired by the Los Angeles Dodgers as their Minor League Field Coordinator.

The Dodgers named McCullough their major league first base coach prior to the 2021 season.