The lesion has a distinctly nested growth pattern with a mixture of spindle, epithelioid and tumor giant cells.

[6] Imaging studies such as X-rays, computed tomography (CT) scans, or MRI may be required to diagnose clear-cell sarcoma together with a physical exam.

Furthermore, a chest CT, a bone scan, and positron emission tomography (PET) may be part of the tests in order to evaluate areas where metastases occur.

Presence of metastasis occurs in more than 50% cases and the common places of its occurrence are the bone, lymph node and lungs.

[9][10] Five-year survival rates, which are reported to be between 50 and 65%, can be misleading because the disease is prone to late metastasis or recurrence.