She acted in short films, including Parker Ellermann's short film Seduction, before landing a role as the title character in the television movie Prinzessin Maleen, which aired on the German channel for Northern Italy.

[9] In August 2020 Von Adelsheim modelled in an advertisement campaign for the fashion line Fleur du Soleil, a collaboration between Sandra Mansour and H&M.

[5] As the Hereditary Princess of Oettingen-Oettingen and Oettingen-Spielberg, Von Adelsheim works with the museum at Schloss Oettingen, one of the family residences.

[11] She is an active member of the Oettingen-Spielberg Family Foundation, which supports underprivileged people in Bavaria.

[6][12] On 9 July 2016 they were married in a religious ceremony at St. Jakob Church in Oettingen in Bayern.

[13][14][15] Princess Isabella Gaetani von Lobkowicz and Beatrice Borromeo served as maids of honour.