Cleopatra III (Ancient Greek: Κλεοπάτρα; c.160–101 BC) was a queen of Egypt.

She is attested as Cleopatra Philometor Soteira (Φιλομήτωρ Σώτειρα) while associated with her eldest son Ptolemy IX.

[2] Cleopatra III's parents retook the throne and remained in power for almost 20 years until 145 BC.

[3][4] Ptolemy VI died in 145 BC from injuries sustained when falling from his horse during the battle of Oinoparas against Alexander Balas.

After 6 years of joint rule Ptolemy X had his mother Cleopatra III murdered in 101 BC.