Clessé (French pronunciation: [klese]; Arpitan: Cllèssié) is a commune in the Saône-et-Loire department in the region of Bourgogne-Franche-Comté in eastern France.

Vineyards of Clessé are part of the appellation d'origine contrôlée Viré-Clessé, which is used for white wines from Chardonnay grapes.

Before 1999, the wines used to be called Mâcon-Clessé.

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