In the fourth season episode "Blind Ambition", an out-of-continuity flashback depicts Cleveland as a fast-talking auctioneer when a totem pole falls over onto his head, resulting in a slower rate of speech.

[3] One of the running gags throughout the series is that Peter's shenanigans frequently destroy the front wall of Cleveland's house, revealing him in the bathtub.

However, even several states away, the Griffins' antics are still seen to cause this event, such as when debris from the missile that Brian, Stewie, Dan Aykroyd and Chevy Chase destroy happens to fall right on Cleveland's new house in the episode "Spies Reminiscent of Us".

In the Cleveland Show episode "Gone with the Wind", the same running gag affects his former wife Loretta Brown, and she breaks her neck on the ground, causing her death.

In "Something, Something, Something Dark Side", this gag is parodied when R2-D2 (played by Cleveland) slips off Luke's (Chris Griffin) X-Wing ship and falls into the swamp after they crash land on Dagobah.

This is shown in the episode "Petarded", when Peter brings seven prostitutes into his house to get back custody of his children and prove to child services that Cleveland is an unfit father.

In the Family Guy episode "Love Blactually", it is suggested that he may have contracted genital warts by having sex with a woman with whom Brian was previously involved.

During a live broadcast of "Loveline", Seth MacFarlane announced that a Family Guy spin-off featuring Cleveland was currently in the works with the studio and writers.

[7] His newly introduced family includes his high school sweetheart, Donna, who is now his second wife, her 15-year-old daughter, Roberta, and her 5-year-old son, Montclair, who goes by his nickname Rallo.

[7] Cleveland was officially written out of Family Guy during Season 8 before The Cleveland Show was broadcast; however, it had been hinted that he might come back for a visit in the future,[11][12] including the episode "Something, Something, Something, Dark Side", although fantasies and film parodies are generally accepted as non-canon Family Guy episodes.

He appeared in a cameo in "Spies Reminiscent of Us", in which he dealt with the indignity of having his new house wrecked in the same fashion as his old one in Quahog, as well as appearing in the season 8 episode "The Splendid Source", where he joins the gang on a road trip to find the source of a dirty joke Chris Griffin told at school.

Another idea had been that Peter Griffin and possibly other Family Guy characters would be traveling in the South and make a guest appearance on The Cleveland Show.

Cleveland and his family appeared in The Simpsons episode "Homerland", as guests into the season 25 premiere who they denied admission at first, the bouncer changes his mind and lets them in.

"[23] Before the 20th season premiere in 2021, Henry sent a video on Twitter saying that he was "handing the torch" to Zahir and said a farewell message in Cleveland's voice.