[2] N'Jie scored his first professional goal against Mladá Boleslav in the third qualifying round of the 2014–15 UEFA Europa League, helping his team to a 2–1 victory.

[10] On 15 August 2015, English side Tottenham Hotspur announced that the club had reached an agreement for the signing of N'Jie from Lyon, subject to international clearance and a work permit.

N'Jie made his Spurs debut on 17 September in a Europa League group stage match against Qarabağ, coming on as a substitute for Andros Townsend.

On 10 December 2015, he tore his medial collateral ligament (MCL) after a challenge by Jérémy Toulalan during a Europa League group stage match against Monaco.

[13] Working with injured teammate Jan Vertonghen during his recovery,[14] N'Jie eventually made his return on 8 May 2016 in a Premier League match against Southampton, in what would be his final appearance of the season.

[15] N'Jie made 8 appearances (all of them as a substitute) for Tottenham in the Premier League, his longest a 79-minute affair when he replaced the injured Nacer Chadli against Liverpool.

[17] Marseille had a €7 million option to buy him at the end of the loan, and Georges-Kévin Nkoudou headed to White Hart Lane on a permanent move in the opposite direction.

[18] On 11 September, he made his debut as a substitute for William Vainqueur in the 68th minute away to Nice, and he scored his first goal two weeks later to equalise in a 2–1 home win against Nantes.