Reiner is one of New York's most influential bar owners,[2] having established the Flatiron Lounge, Lani Kai, and the Clover Club.
Major publications have featured Reiner's drink recipes, including The Wall Street Journal, Playboy, Esquire, GQ, and Time Out London.
[4] At the Flatiron Lounge, the staff nicknamed Reiner "Destroyer of Dreams", while her partner Fedroff was "Creator of False Hopes".
Romee de Goriainoff, who opened the first modern cocktail bar in Paris, said of the Flatiron Lounge, "it's the one I got the most inspiration from".
[5]: 152–153 The Flatiron Lounge, which Reiner opened with her partners in May 2003, is credited with helping to popularize the craft cocktail movement in New York.
In 2015, Reiner partnered with Ivy Mix to open the bar Leyenda across the street from the Clover Club.
[3] In September, 2022, Reiner and partners Christine Williams, Susan Fedroff, and Sam Sherman, reopened SoHo bar Milady's.
[15] Drinks International's 50 best bars in the world included Clover Club on the list for two consecutive years.