Founded in 1914, the club's home venue is Estadio Luis Alberto Salinas Tanasio.

[5] Despite losing the finals, their overall standing, which was first in the aggregate table, gave them a spot in the 2003 Copa Libertadores, where they were knocked out by finishing last in the group stage and only winning one game against Ecuador's El Nacional.

In 2007, 12 de Octubre arrived to the last matchday of the Clausura, after having a poor season, one step away from being relegated.

At halftime in the second leg, the score was 2-2 (3-4 on aggregate), which put 12 de Octubre in a tough position again.

However, with great effort and the support from the fans, they turned things around by winning the game 4-2 (5-4 on aggregate) with goals from Hugo Notario, Francisco Esteche, Diego Miranda, and Domingo Ortiz.

This meant that 12 de Octubre was relegated to the Segunda Division after 11 years in the top flight.

It finished runner-up behind champion 3 de Febrero, and achieved promotion back to the top tier for the 2014 season.

[9][10] Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.