[2] The Clarksdale, MS Micropolitan Statistical Area includes all of Coahoma County.

[3] The Memphis-Clarksdale-Forrest City Combined Statistical Area has a population of roughly 1.4 million.

Coahoma County was established February 9, 1836, and is located in the northwestern part of the state in the fertile Yazoo Delta region.

[7] In 1841, high waters on the Mississippi River flooded Port Royal, and in 1842 the county seat was moved to the town of Delta.

As nearby Clarksdale grew in population and influence, it challenged Friars Point's hold on the county government, and in 1892, Coahoma County was divided into two jurisdictions, one going to Friars Point and the other to Clarksdale.

[10] As of the 2020 United States Census, there were 21,390 people, 8,782 households, and 5,637 families residing in the county.

Coahoma County was previously in the service area of the Mississippi Delta Community College (MDCC).

As a result of the 1995 Mississippi Legislature session, Coahoma County is no longer in the MDCC service area.