Midori tells him the story of how women on Cobra Island are disappearing at a rapid rate and the mob boss of the Black Gang, Hōmura, is believed to be the one causing it.

[13] Aktueller Software Markt's Marcus Höfer commended the audiovisual presentation but panned the controls, atmosphere and lack of additional story paths, regarding the animations and visuals to be the game's only main driving force.

[4] PC Joker's Monika Stoschek commended the mouse controls and menus for being easy to use but regarded the gameplay to be repetitive and the visuals as poor, stating that the "half-naked females presented in between are probably a matter of taste.

"[10] PC Player's Heinrich Lenhardt also criticized the gameplay for being bland and high retail price, stating that it would go under as a "gray RPG" without the mild sex and crime factors.

[5] They found the explicit nudity, sexual connotations and foul language unsuitable, while criticizing the animations and English translation but commended the graphics for being faithful to the Japanese original.

[5] PC Games' Thomas Brenner disagreed with the statement of Dragon's reviewers, doubting that Cobra Mission could be harmful to young players as advertised on the packaging.

praised its sense of humor, erotism, comic-like presentation, graphics, sound and animations but felt mixed in regard to the originality and criticized the low difficulty, while warning that the sexual content on-display makes it unsuitable for younger audiences.