Mizell attended Clemson University, where he was first choice goalkeeper for all three seasons, winning numerous All-American and All-ACC awards as a Tiger.

[6] After making five appearances for the Rowdies in 2014, Mizell and Tampa Bay exercised an option in his contract to terminate it to explore future club considerations.

[11] On November 6, 2018, New Mexico United announced Cody Mizell as one of the first six signed players in club history, under the guidance of Head Coach Troy Lesesne.

[citation needed] On March 4, 2021, Mizell was purchased by Major League Soccer club New York City FC for an undisclosed transfer fee, signing him through the 2022 season.

Mizell capped multiple times for the U.S. under-17 national team, making his debut against England U17 at the 35th Mondial Minimes International Tournament in Les Essarts, France.