Common hosts of the plant include tropical trees and shrubs, with the following being the more common or economically important; tea, kava, pepper, para rubber, magnolia, coffee, holly, Indian hawthorn, oil palm, avocado, vanilla, mango, breadfruit, guava, coconut, cashews, cacao, citrus, etc.

While usually harmless, severe causes of these leaf spots can lead to defoliation, twig dieback, tissue necrosis, and loss of marketable fruit.

Algal filaments extend from these thalli further increasing the surface area this pathogen infects.

[1][3] Often, leaf spot caused by Cephaleuros virescens is not damaging enough to the host plant's vigor or crop yield and therefore generally does not warrant management.

If however the crop is highly susceptible, a form of integrated pest management can be used to prevent the spread and infection of the disease.

[2] Guava is considered to be a susceptible host, and the leaf spot symptoms can grow to be severe enough to reduce plant vigor and cause defoliation.

In guava, Cephaleuros virescens can cause fruit spots as well, leading to a reduction in crop yield.