The team re-examines the 1995 murder of homeless 17-year-old amateur skateboarding prodigy Nash Simpson, who was trying to earn enough money through skating sponsors to get himself off the street, after his brother identifies his belongings upon arriving in Philadelphia.
The team reinvestigates the 1970 murder of Billy Sanders, a 20-year-old virtuoso jazz musician who was keeping his hard-partying lifestyle secret from his devoutly religious father, when his son arrives wanting to know more about him, having been born after his death.
The team reinvestigates the 1991 murder of Donalyn Sullivan, a 14-year-old aspiring rapper who was in foster care with her younger sister at the time of her death, when a convict discloses information that leads them to the primary crime scene.
The team reopens the case of Harry Denton, a private investigator who was murdered in 1974 while working to track down a teenage runaway, when his bones are found in the cement foundations of a demolished building.
The resident police expert on fires and explosions, Louie Amante, is going to marry a woman whose previous fiancé, Dan Palmer, mysteriously died in 2008 after calling off their wedding.
[16] The team reopens the case of Mick "The Machine" Malone, a 28-year-old dock worker and young father who was moonlighting as an indy-circuit wrestler until he was shot dead in 1986, when the gun used to kill him is recovered.
Realizing that the missing Vera has finally hit rock bottom, his worried team members hope that a new twist to a 2006 arson case that killed two boys and brothers, which he was secretly obsessing about in recent weeks, might supply leads to his whereabouts.
After determining the serial killer's identity - and some of his likely future targets - the team and the FBI work together to apprehend him while trying to locate and protect the people he's preparing to kill.