CSHL Press publishes monographs, technical manuals, handbooks, review volumes, conference proceedings, scholarly journals and videotapes.
Revenue from sales of CSHL Press publications is used solely in support of research at Cold Spring Harbor Laboratory.
The series began in 1970 with The Lactose Operon edited by David Zipser and Jonathan Beckwith OCLC 67611756 CSHL Press has two operation centers.
The main office is located in Woodbury, New York, near Cold Spring Harbor Laboratory, where editorial, marketing & advertising, composition, and fulfillment & distribution functions are performed.
An additional book fulfillment & distribution operation is handled by NBN International in Plymouth, United Kingdom.