He is best known for his television work hosting and co-writing The Blizzard of Odd, The Unbelievable Truth, and as resident panellist on The Blame Game for BBC Northern Ireland and The Panel for RTÉ.
He has also acted in the film Divorcing Jack with Rachel Griffiths and David Thewlis.
Murphy mainly tours in Ireland and usually hosts the comedy show in The Empire Bar, Belfast.
He occasionally appears at other venues in the UK such as the Edinburgh Fringe Festival, and has performed at Kilkenny Cat Laughs, Melbourne Comedy Festival, and Just for Laughs.
Murphy has appeared on the following programmes:[citation needed] Murphy has done charity work for Plan Ireland, including making a film about work done by the charity.