Colnbrook with Poyle is a civil parish in the borough of Slough in Berkshire, England.

Located approximately 17 miles (27 km) west of central London and adjacent to the Greater London boundary, it is an urbanised parish with some industrial development and open land.

Most of Colnbrook had been from 1974 in the parish of Iver in South Bucks district in Buckinghamshire, and before 1974 had been mostly in the parish of Horton, with small areas in Langley Marish.

Poyle had been in the unparished borough of Spelthorne in Surrey (before 1974 forming part of the Staines Urban District of Surrey which had transferred from Middlesex in 1965).

[3] It is at the eastern end of the borough of Slough, and is just to the west of the M25 motorway, which separates the parish from Heathrow Airport in the London Borough of Hillingdon in Greater London.