The film stars Zoe Saldaña[2] with supporting roles by Michael Vartan, Cliff Curtis, Lennie James, Callum Blue, and Jordi Mollà.

Fabio gives his nine-year-old daughter, Cataleya, a SmartMedia computer memory card loaded with information on Don Luis' business and tells her it's her "passport"; he also gives her the address of her uncle Emilio in Chicago, Illinois, who will take care of her.

Although American officials attempt to transfer her into the foster care system, Cataleya tracks down her uncle in Chicago and asks him to train her as a killer.

With each murder she commits, she leaves her signature, the Cattleya flower, hoping to one day attract the attention of Don Luis so she can take her revenge.

While she is spending the night with her American boyfriend, Danny Delanay, he takes a photo of her sleeping and then shows it to a friend, who then decides to run a background check on Cataleya, which alerts the FBI.

She confronts Ross at his home and threatens to kill him and his entire family, forcing him to reach out to CIA agent Steve Richard, who she knows is sheltering Don Luis from the law in exchange for his cooperation with American authorities.

Don Luis learns that Cataleya is still alive and organizes his men to kill her, but she ambushes them first and wipes out the entire gang, including Marco.

[9] Christy Lemire of The Associated Press reviewed Colombiana, writing that "The director of La Femme Nikita and The Fifth Element serves as co-writer and producer here, but this is very much a spin-off of his brand, a continuation of the kind of stereotype- and gravity-defying characters he's made his name on.

"[12] Jordan Mintzer of The Hollywood Reporter, said that "There are guilty pleasures to be had in this frenzied B starring Zoe Saldaña, who gives an acrobatic performance that makes the overcooked material watchable.

"[14] The following year, in an essay published in Senses of Cinema, David Martin-Jones focused on a different aspect of the South American character, believing that the film provided "a different perspective" concerning immigration and international wealth inequality.