Hardy Murfree (June 5, 1752 – April 6, 1809) was a lieutenant colonel from North Carolina during the American Revolutionary War.

Murfree, a lieutenant in the Hertford County militia when the Revolutionary War began, was commissioned on September 1, 1775, as a captain in the 2nd North Carolina Regiment of the Continental Army.

He was then a major serving under General Anthony Wayne, and was soon thereafter promoted to lieutenant colonel.

[2] Around 1807, Murfree migrated to Williamson County, Tennessee, living on land granted to him after the American Revolution, and remained there until his death in 1809.

In 1811 the Tennessee State Legislature renamed the town of Cannonsburgh to Murfreesborough (later shortened to Murfreesboro) in his honor.