These byways follow existing roads or highways and are signed with a Colorado blue columbine (the Colorado state flower) logo denoting the route.

Since 1989, the program has designated 26 Colorado Scenic and Historic Byways with 2,585 miles (4,160 km) of roadway, 4,459 miles (7,176 km) including scenic byway extensions in adjacent states.

In addition to state scenic byway designations, four federal agencies designate specific types of scenic byways: The Colorado Scenic and Historic Byways Commission works closely with these four federal agencies to select scenic and historic byways that meet federal criteria.

[7] The 13 combined All-American Roads and National Scenic Byways in Colorado are currently the most of any state.

[9] The program is a statewide partnership intended to provide recreational, educational, and economic benefits to residents and visitors by designating, interpreting, protecting, and promoting a system of outstanding touring routes in Colorado.Proposed routes are nominated by local communities and approved by the Commission, but byway development is managed at the local level.