SH 116's western terminus is at U.S. Route 287 (US 287) and US 385 near Springfield, and the eastern terminus is at W Road 12 at the Kansas state line.

The highway gives service though the very rural country in Baca County through Two Buttes to the junction with US 287 and US 385 about 7 miles north of Springfield.

The highway's maintenance is served by Two Buttes, the only town on its route.

The entire route is in Baca County.

[2] Media related to Colorado State Highway 116 at Wikimedia Commons