Christopher Columbus O'Donnell (October 1, 1792 – May 26, 1873) was an American businessman who served as president of Baltimore's Gas and Light Company.

"[3] His father likely arrived in Baltimore around 1785, eventually acquiring a 1,981 acre estate that he called Canton, that "wound around the elbow of the northwest branch of the Patapsco River, east of Fell's Point."

He also bought more than 100 lots in Baltimore, the two Miller Islands in the Chesapeake Bay, a 1,628 estate in Howard County known as Never Die, and 3,000 acres in Virginia.

"[3] The bill passed in 1829 and the company was given the right to lay out streets, build wharves, ships, factories, stores and homes, which O'Donnell did together with William Patterson and Peter Cooper.

[25] In his will, he left his estate to his children and grandchildren, with specific bequests of $5,000 to the Maryland Institution for the Instruction of the Blind, $5,000 to St. Mary's Industrial School for Boys, and $5,000 to the Roman Catholic Asylum for Widows.