Roasters: Courtney Love, Adam Carolla, Bea Arthur, Nick DiPaolo, Greg Giraldo, Elon Gold, Eddie Griffin, Lady Bunny, Lisa Lampanelli, Tommy Lee, Jeff Ross, Sarah Silverman, and Andy Dick, with pre-taped appearances by David Spade and Hugh Hefner.

Roasters: Andy Dick (as the "love child" of James T. Kirk and Spock), Farrah Fawcett, Greg Giraldo, Lisa Lampanelli, Artie Lange, Nichelle Nichols, Patton Oswalt, Kevin Pollak, Jeff Ross, George Takei, Betty White, and Fred Willard performing the roasting duties.

Notable audience members: Andy Daly, Adrian Zmed, David Carradine, Roger Corman, Brent Spiner, Jeri Ryan, René Auberjonois, Rosalind Chao, Mark Valley, Carrie Fisher, Scott Hamilton, Brad Paisley, Reno 911!

[citation needed] Roasters: Ice-T, Jimmy Kimmel, Snoop Dogg, Greg Giraldo, Patton Oswalt, Lisa Lampanelli, Jeff Ross, Carrot Top, Sommore, and Brigitte Nielsen.

Roasters: Carl Reiner, Gilbert Gottfried, Mario Cantone, Whitney Cummings, Tom Arnold, Brad Garrett, Robin Quivers, Greg Giraldo and Jeff Ross.

[citation needed] Roasters: Jeff Ross, Pamela Anderson, Lisa Lampanelli, Hulk Hogan, Jerry Springer,[24] Whitney Cummings, Greg Giraldo, George Hamilton,[25] and Gilbert Gottfried, Sharon Osbourne and Piers Morgan made pre-taped appearances, and William Daniels reprised his role as the voice of KITT.

Notable audience members: John Slattery, Craig Robinson, Christina Milian, Hasselhoff's two daughters, Hayley and Taylor, Hulk Hogan's son, Nick, and fellow Baywatch alumni Alexandra Paul, Nicole Eggert, Gena Lee Nolin, Traci Bingham, Angelica Bridges and Jeremy Jackson.

[29] Roasters: Anthony Jeselnik, Jon Lovitz, Patrice O'Neal, Jeff Ross, Amy Schumer, William Shatner, Steve-O,[33] Mike Tyson, and Kate Walsh.

Notable audience members: Brooke Mueller, Aaron Paul, Slash, Maria Menounos, Corbin Bernsen, Duane Chapman, Kevin Cronin of REO Speedwagon, Michael Boatman, Kristin Cavallari, Ciara Hanna, Wayne Federman, Richard Kind, Ron Jeremy, and Patrick Warburton.

[citation needed] The roast was taped in Los Angeles on September 10, 2011, and was broadcast nine days later, exactly one hour after the premiere of Ashton Kutcher's first episode on Two and a Half Men where he replaced Sheen.

Roasters: Ellen Barkin, Wayne Brady, Carrie Fisher, Gilbert Gottfried, Seth Green, Anthony Jeselnik, Jeff Ross, Katey Sagal, and Amy Schumer, and also featured a surprise appearance by Barr's ex-husband Tom Arnold.

[39] Notable audience members: Sarah Chalke, Natasha Leggero, Blake Anderson, Wayne Federman, Alicia Goranson, Michael Fishman, Frances Fisher, Tyler, the Creator, Traci Lords, Chris Colfer, Caroline Rhea and Fred Willard.

[citation needed] Roasters: Aziz Ansari, Bill Hader, Jonah Hill, Nick Kroll, Natasha Leggero, Jeff Ross, Andy Samberg, and Sarah Silverman.

[43] Notable audience members: DeAndre Jordan, Blake Anderson, Jillian Bell, Adam DeVine, Andy Dick, Chris Farren, Wayne Federman, Dave Franco, Jennie Garth, Brett Gelman, Eiza González, Anders Holm, Gabriel Iglesias, Kelley Jakle, Samm Levine, Maribeth Monroe, Matthew Morrison, Amy Poehler, Stephen Rannazzisi, June Diane Raphael, Retta, Horatio Sanz, Paul Scheer, and Kate Walsh.

Roasters: Hannibal Buress, Pete Davidson, Chris D'Elia, Will Ferrell as Ron Burgundy, Natasha Leggero, Ludacris, Shaquille O'Neal, Jeff Ross, Snoop Dogg, and Martha Stewart.

[45][46] Notable audience members: Scooter Braun, Dave Chappelle, Tito Ortiz, John Legend, Chrissy Teigen, Kendall Jenner, Wayne Federman, Jack Gilinsky, Blake Anderson, Katharine McPhee, Kourtney Kardashian, Kate Walsh, Chris Paul, Trevor Noah, Sarah Tiana, Larissa Marolt, Carly Rae Jepsen, Jaden Smith, Gloria Allred and Kyle Kinane.

[48] Roasters: Jimmy Carr, Ann Coulter,[50] Pete Davidson, Nikki Glaser, Jewel, Ralph Macchio, Peyton Manning, Rob Riggle, Jeff Ross.

Notable audience members: Maria Shriver, Patrick Schwarzenegger, Nick Swardson, Fred Savage, Chad Lowe, Kate Walsh, Robbie Williams, Brandon Flowers, Marlee Matlin Roasters: Cybill Shepherd, Edward Norton, Nikki Glaser, Lil Rel Howery, Dom Irrera, Kevin Pollak, Dennis Rodman, Martha Stewart[56] and Jeff Ross.

[58] Roasters: Robert De Niro, Blake Griffin, Caitlyn Jenner, Chris Redd, Jeff Ross, Ken Jeong, Nikki Glaser, Caroline Rhea, Adam Carolla.