Comics Unleashed is a half-hour comedy talk show produced by the Entertainment Studios production company and hosted by Byron Allen, with John Cramer as announcer and DJ Cobra or sometimes DJ A1 providing music support.

Each episode begins with Allen delivering a short, usually topical monologue, after which he introduces the night's DJ and the panel of four comedians.

First-run weekly episodes were originally produced from 2006–07, with repeats still airing in some markets, generally in the very late-night to overnight hours under bulk barter arrangements made for the various series of Entertainment Studios, with some notable carriers having included CBS Television Stations (which scheduled it as a lead-out for The Late Late Show on CBS owned-and-operated stations).

[1] Back-to-back episodes also aired in prime time on MyNetworkTV before it became a programming service.

This article relating to a comedy television series in the United States is a stub.