Specifically, the absence of a fully developed corpus callosum is shown to have a significant relationship with impaired verbal processing speed and problem solving.

[3] Another study of individuals with multiple sclerosis provides evidence that structural and microstructural abnormalities of the corpus callosum are related to cognitive dysfunction.

Particularly, verbal and visual memory, information processing speed, and executive tasks were shown to be impaired when compared to healthy individuals.

[4] Using diffusion tensor imaging, researchers have been able to produce a visualization of this network of fibers, which shows the corpus callosum has an anteroposterior topographical organization that is uniform with the cerebral cortex.

The anterior commissure (also known as the precommissure) is a tract that connects the two temporal lobes of the cerebral hemispheres across the midline, and placed in front of the columns of the fornix.

A case study described recently in The Irish Medical Journal discussed the role the posterior commissure plays in the connection between the right occipital cortex and the language centers in the left hemisphere.

It is evident from this case study of alexia without agraphia that the posterior commissure plays a vital role in transferring information from the right occipital cortex to the language centers of the left hemisphere.

White matter degeneration of the genu of the corpus callosum is also associated with gait, balance impairment, and the quality of postural control.