Comstock is an unincorporated community located in Val Verde County, Texas, United States, approximately 20 miles northwest of Del Rio on U.S. 90.

Comstock was founded circa 1883 on the Galveston, Harrisburg and San Antonio Railway as the line drove west toward El Paso.

Comstock was at the height of its activity between 1888 and 1910, when the Deaton Stage Line operated between the town's railroad depot and the city of Ozona, some 60 mi (100 km) north.

Amtrak’s Sunset Limited passes through the town on Union Pacific tracks, but makes no stop.

Seminole Canyon State Park and Historic Site has cave drawings and other evidence of settlement dating from the early Archaic period, around 7000 BC.