Conception Junction is a city in southeastern Nodaway County, Missouri, United States.

According to the United States Census Bureau, the city has a total area of 0.31 square miles (0.80 km2), all land.

There were 97 housing units at an average density of 312.9 per square mile (120.8/km2).

33.3% of all households were made up of individuals, and 12.8% had someone living alone who was 65 years of age or older.

32.5% of all households were made up of individuals, and 22.9% had someone living alone who was 65 years of age or older.

About 8.8% of families and 15.3% of the population were below the poverty line, including 22.2% of those under the age of eighteen and 21.4% of those 65 or over.