In November 1957, representatives of the fraternities Phi Eta Mu, Phi Sigma Alpha, and Nu Sigma Beta met at the latter's clubhouse in Cupey Alto, Rio Piedras, Puerto Rico to found a Greek letter umbrella organization.

By July 1964, Alpha Beta Chi and Phi Delta Gamma had joined Concilio Interfraternitario de Puerto Rico as well.

[2] As of 2024, the two oldest sororities in Puerto Rico, Mu Alpha Phi and Eta Gamma Delta, are also members.

On August 29 and 30 of 1958, a congress was held with activities in the headquarters of all three original organizations in San Juan, Puerto Rico.

[3] The congress established that the ideals of the CIPR were: “To recognize brotherhood amongst men with the aim of achieving mutual understanding, tolerance and respect; to put into practice the ideals of brotherhood and selfless friendship, thus eliminating the barriers of harm between men; to promote the development of moral values and the ideal of service in man”.