In March 1928 a group of young ladies enrolled in the University of Puerto Rico at Rio Piedras founded Eta Gamma Delta Sorority.

[1] During the presidency of Beatriz del Toro in 1929, the sorority was recognized by university authorities.

By 1932, an alumnus chapter called "Capitulo Pasivo" was organized in San Juan during the presidency of Conchita Santana Campos.

In 1940, on the (Colegio de Agricultura y Artes Mecanicas) now the University of Puerto Rico at Mayagüez Gilda Cernuda, Socorro Gaztambide, Aida Gauthier, Iris Ramírez, Catín Rllán, Doris Pérez, and others founded Delta Phi Omega sorority, it was the first sorority at the campus.

In 1944, the first Directiva General or central office was established, with Eleonor Lawton as its first president.

[1] In 1955 an alumnus chapter - Zona - was founded at Ponce; its first president was Práxes Torres de García.