In the early 1960s, the LCMS purchased the Earhart Manor and surrounding estate in Ann Arbor and began construction of Concordia Lutheran Junior College.

In 1977, Concordia began performing the "Boars Head Festival", an annual Christmas celebration filled with song, music, and drama that is much beloved by current students, alumni, and community members.

[4] The merger became effective on July 1, 2013, with Curt Gielow, former executive dean of CUW's School of Pharmacy and former mayor of Mequon, Wisconsin, becoming Vice President of Administration and Chief Campus Officer at CUAA.

[8] In mid-February 2024 local news sources reported that Ankerberg had alerted the students, faculty, and staff that the university's financial situation was forcing the Ann Arbor campus's mission to be "re-imagined", likely leading to significant reductions in the programs and the sale of some of the equipment and property.

[9] John Berg, chairman of the board, released a video stating that the campus would remain at full operations for the 2024-2025 academic year.

They are also a member of the National Christian College Athletic Association (NCCAA), primarily competing as an independent in the Midwest Region of the Division I level.