Conewago Creek is an 80.2-mile-long (129.1 km)[1] tributary of the Susquehanna River in Adams and York counties in Pennsylvania in the United States, with its watershed also draining a small portion of Carroll County, Maryland.

The source is at an elevation of 1,440 feet (440 m), east of Caledonia State Park, in Franklin Township in Adams County.

[7] The Conewago Creek watershed has a total area of 515 square miles (1,330 km2) and is part of the larger Chesapeake Bay drainage basin via the Susquehanna River.

Further downstream in Adams County there is a small "catch and release" section of the creek.

[10] The creek is home to a variety of fish including smallmouth bass, walleye, bluegill, rock bass, sunfish, carp, channel catfish, flathead catfish, yellow perch, rainbow trout, muskellunge and crappie.