According to tradition, Constantius had to deal with a diocese possessed by demons; he sent to Benedict of Nursia in the monastery of Montecassino, who then drove out the devil with his prayers.
During his tenure, Constantius experienced the destruction of the city in the war between Byzantium and the Goths at around 550; many residents were killed, others died of a plague.
[3] A codification of the order of pericopes in a lectionary was dedicated to Constantius by Victor of Capua.
Gregory also records his last prophecy: on his deathbed Constantius foretold that he would be succeeded by a muleteer and a washerman, after which Aquino would have no more bishops.
Many of the inhabitants were killed by the invaders, and many more died of a plague, and there was no-one left fit to be bishop, whereby Constantius's prophecy was fulfilled.