Controlled substance

This incorrect view may be further re-enforced by R&D chemical suppliers often stating and asking scientists to confirm that anything bought is for research use only.

These either provide detailed descriptions similar to Markushes, or simply state analogues are also controlled.

Due to this complexity in legislation the identification of controlled chemicals in research is often carried out computationally, either by in house systems maintained a company's sample logistics department or by the use commercial software solutions.

In addition, import or export authorization is not required in case of controlled substances for analytical purpose in concentrations up to 1 mg/ml.

However, the associated Misuse of Drugs Regulations 2001[6] does exempt products containing less than 1 mg of a controlled substance (1 ug for lysergide and derivatives) so long as a number of requirements are met, including that it cannot be recovered by readily applicable means, does not pose a risk to human health and is not meant for administration to a human or animal.

In 2017 the Home Office also confirmed that the 1 mg limit applies to the total of all preparations across the entire container in the case of sample microtitre plates.

[7] United States of America In the US no general research exemptions are known to exist, at least at the federal level and the Controlled Substances Act.

Also whether the ‘0.001%’ allows the rest to be an assay solvent or medium, or whether a licence is needed if you have some solid, e.g. 1 mg of sample before its diluted is not clear.