Cool Center is a Philippine television comedy talk show broadcast by GMA Network.

Hosted by Eugene Domingo and Anjo Yllana, it premiered on March 14, 2009.

The show concluded on April 17, 2010 with a total of 55 episodes.

According to AGB Nielsen Philippines' Mega Manila household television ratings, the pilot episode of Cool Center earned a 13.9% rating.

This Philippine television program-related article is a stub.