The Coordination Centre for Health Alerts and Emergencies (Spanish: Centro de Coordinación de Alertas y Emergencias Sanitarias, CCAES) is a body of the Spanish Ministry of Health responsible for coordinating the management of information and supporting all health authorities in cases of national or international health alert or emergency situations that pose a threat to the health of the population.

The CCAES was created in 2004, under minister Ana Pastor Julián.

It is led by a Director, currently Fernando Simón since 2012.

[1] The responsibilities of the CCASE are regulated in two legal instruments, the founding ministerial order of the centre and the current Royal Decree that establishes the Ministry's structure.

According to the Order of the Minister of Health of 27 February 2004, the centre has five main responsibilities:[2] According to the Royal Decree 454/2020, which develops the basic organic structure of the Ministry of Health, the centre's duties are also:[3]