[11] They played their first game there on 14 August 2013 in front of a sell-out crowd, losing 72–107 to the Iowa Hawkeyes American college basketball team in an exhibition match.

[citation needed] The Copper Box hosted the London Grand Prix badminton tournament on 1–6 October 2013.

[14] The floor was badly damaged during a mass fitness event in January 2014, resulting in several netball internationals having to be played elsewhere at the last minute.

[15] Counter-Strike: Global Offensive and Super Smash Bros. Melee DreamHack London 2015 took place at the Copper Box on 19–20 September.

Morales, a player on NRG, scored a last-second goal that forced overtime in game 7 of the World Championship Grand Final Bracket Reset.

The RLCS would return to the Copper Box for the 2021–2022 season Spring Major on 29 June–3 July 2022, with crowds only being present on the final two days.

[21] Great Britain played Kazakhstan at the arena in April 2019, in the tennis Fed Cup World Group II play-offs.

[24] Between January and July 2020, the Copper Box Arena was used as the home venue for the London Royal Ravens, an eSports team taking part in the inaugural Call of Duty League.

In November 2023, the arena was used for the 2023 Billie Jean King Cup play-offs between Great Britain and Sweden, which determine which team is relegated below the qualifying rounds in 2024.