[1] This could result in the early development of arcus lipoides, hazy corneal limbus, and hyperopia.
[2] There is evidence that cornea plana 2 is caused by mutations in KERA gene encoding keratocan.
[2] Although a small corneal diameter is anticipated, measuring it can be challenging because the scleral tissue overlaps the cornea by a few millimeters.
In the patients who have cornea plana, the anterior chamber depth has been found to vary from 0.8 to 2.1 mm.
[5] Histology is distinguished by acanthosis, keratinization of the corneal epithelium, Bowman's membrane defects, and stromal vascularization and scar formation.