A coloboma (from the Greek κολόβωμα, meaning "defect")[1] is a hole in one of the structures of the eye, such as the iris, retina, choroid, or optic disc.

Commonly posterior colobomata affect the inferior retina, with resultant deficit in the superior visual field.

[3] Eye abnormalities have been shown to occur in over 90% of children with fetal alcohol syndrome.

Vision can be improved with glasses, contact lenses or even laser eye surgery but may be limited if the retina is affected or there is amblyopia.

[6] Notable people with coloboma include actor John Ritter, model/actress Karolina Wydra, The New York Times columnist Andrew Ross Sorkin, pop singer songwriter Lachi, U.S. Olympic medalist Stephen Nedoroscik, and George Soros.