He worked at various times with Aretha Franklin, Bill Withers, Donny Hathaway, King Curtis, and Steve Gadd, appeared on Late Night with David Letterman,[2] and wrote a book on soul and blues guitar, Rhythm and Blues Guitar.

[7] Dupree and other East Coast jazz fusion musicians played on Van McCoy's hit 1975 single "The Hustle".

In the late 1970s, Dupree formed the new jazz fusion group Stuff[2] with Eric Gale, Richard Tee, Steve Gadd, Chris Parker, and Gordon Edwards.

The scene also shows Dupree playing guitar on a stool while breathing with an oxygen tank, foreshadowing his battles with emphysema.

[9] With Gadd Gang With Rainbow With Stuff With Joe Cocker With Hank Crawford With Aretha Franklin With Donny Hathaway With The Joneses With Margie Joseph With King Curtis With Roland Kirk With Van McCoy With Geoff Muldaur With David "Fathead" Newman With Esther Phillips With Wilson Pickett With Lou Rawls With Archie Shepp With Stanley Turrentine With Zulema With others