In neuroanatomy, the corona radiata is a white matter sheet that continues inferiorly as the internal capsule and superiorly as the centrum semiovale.

Evidence from subcortical small infarcts suggests that motor fibers are somatotopically arranged in the human corona radiata.

Following subtotal brain damage, localization of the corticofugal projection in the corona radiata and internal capsule can assist in evaluating a patient's residual motor capacity and predicting their potential for functional restitution.

Findings also suggest that motor deficit severity is likely to increase as a lesion occupies progressively more posterior regions of the internal capsule.

[citation needed] In normal pressure hydrocephalus, expansion of the lateral ventricles causes distortion of the fibers of the corona radiata.