He is best known today for having created the role of Ismaele in Verdi's opera Nabucco, although he sang in the world premieres of several other lesser-known works.

Little has been recorded of his life and career prior to his performance in the world premiere of Nabucco in March 1842, apart from his appearance earlier that year as Ivanhoe in Nicolai's Il templario at the Teatro Sociale in Mantua.

[1][3] Of the major Italian opera houses, he appeared at the Teatro San Carlo in Naples in the 1850 season singing the title role in Vincenzo Moscuzza's Stradella il trovatore, Lindoro in L'italiana in Algeri, and Ernesto in Don Pasquale, and appeared at the Teatro Regio in Turin in the 1853 carnival season singing Aménophis in Mosè in Egitto and the title role in Pacini's Buondelmonte.

[4] During this time, an album of seven songs for voice and piano entitled Una notte sul Tago and composed by Miraglia on themes from his native Sicily was published in Lisbon.

[7] In the last ten years of his life, Miraglia taught singing (amongst his pupils were Francisco and António D'Andrade) and also worked as a theatrical agent, occupying much of his time with the careers of his niece Teresina Brambilla and her husband, the composer Amilcare Ponchielli.