In 1975, he joined with members of Osanna, including his brother Danilo, to form the group Nova.

For the next two albums Vimana (1976) and Wings of Love (1977), they relocated to London and worked with prominent members of the progressive rock and jazz fusion scenes, including Narada Michael Walden and Phil Collins.

After the disbandment of Nova, Rustici moved to Los Angeles and started a successful career as a producer and musician collaborating with many artists both in the United States and Italy.

His 2006 album, Deconstruction of a Postmodern Musician, features guest artists such as Elisa and Allan Holdsworth.

[2] In 2021, Rustici released the album Interfulgent and a single called "The Singing Light" in memory of his brother Danilo.