The station launched on March 14, 2006 as a collaboration between SIRIUS Satellite Radio and Cosmopolitan magazine.

The programs featured everything that Cosmopolitan offered like advice on sex, love, and relationships, beauty and fashion tips, celebrity news and music.

Programming on Cosmo Radio included interviews with Cosmopolitan's expert editors, including Editor in Chief Kate White, on everything from astrological predictions to snagging the man of your dreams.

The shows also featured celebrity guests talking about their latest projects as well as readers sharing their own experiences.

The last day that Cosmo Radio was broadcast was Friday, October 25.