Cottage Grove Avenue Presbyterian Church is a historic building located in Des Moines, Iowa, United States.

The building is a trapezoid, matching its lot, and features a veneer of Bedford stone and a flat roof.

At about the same time as the present sanctuary was built, the congregation began to take on the Progressive ideals of social reform and community service.

The congregation's name change suggests its commitment to the neighborhood, and the new sanctuary does not have any traditional church embellishments on the exterior, but that of a home.

William Burton Sanford and James Thompson Mordy the congregation took on the issues of restricted residential zoning in the area, the Negro Community Center, and youth programs.