It was built by the Coudersport and Port Allegany Railroad in 1899 and opened in January 1900 during the lumber industry boom in Potter County.

[3] The original plan for a railroad along the Allegheny River between Coudersport and Port Allegany was as a part of the Jersey Shore, Pine Creek and Buffalo Railway (JSPC&B), which was incorporated on February 17, 1870.

The JSPC&B was originally planned to run from the vicinity of Williamsport west to Jersey Shore, then north up Pine Creek and down the Allegheny River past Coudersport and west to Port Allegany,[4] as part of a larger route to Buffalo, New York.

[5][6] In the early 1880s the route along the Allegheny River was sold and in October 1882 the narrow gauge Coudersport and Port Allegany Railroad opened on the 17-mile (27 km) line between Coudersport and Port Allegany.

The railroad was converted to standard gauge in 1889 and six years later the line was extended east to Newfield Junction (where it connected with the Buffalo and Susquehanna Railroad) and then on to a new eastern terminus at Ulysses, where it linked with the Fall Brook Railway.

[7] The Coudersport and Port Allegany Railroad began construction on a new station in 1899 and opened it in January 1900.

[10] The Coudersport and Port Allegany Railroad Station is built of red brick and local sandstone.