This segment of CR 10A is named Old Highway 90, and at first, runs along the north side of the CSX P&A Subdivision.

The road maintains the name "Old Spanish Trail" as it enters Holmes County from the Walton-Holmes County Line, briefly turning north and south on the east side of that border only to curve briefly to the east after one power line right-of-way where it then crosses a second power line right-of-way before turning northeast, and winding through the woods of southwestern Holmes County.

Continuing southeast, the road runs through more woods interrupted by two parcels of farmland on the south side, obstructed by a line of trees with a grass road between the two farms, then crosses the first power line right-of-way it went under when it entered Holmes County.

Avoiding a fork in the road, CR 10A makes a sharp right turn to end at US 90 and the Baker Manning Loop.

The second segment begins in eastern Ponce De Leon at US 90 east of Main Street.

The first name of this segment is Old US 90, and runs northeast of US 90 from there until it reaches Oak Grove Church Road, then turns southwest until it terminates at US 90 in rural western Holmes County.

CR 10A doesn't truly enter the city limits until it approaches the headquarters of Jackson County Transportation on the northwest corner of Sunrise Drive.

After CR 286, the road runs along the north side of the P&A Subdivision, across from Sneads High School.

The former right-of-way for the Old Spanish Trail runs along the south side of US 90 as it crosses Pete's Way and then Barannie Lane just before it ends.

Within the city, most of the area surrounding the route is purely residential, except on the northwest and northeast corners of White Avenue, and other random locations.

Drivers know that they're about to leave the city when they see a storage facility on the southwest corner of Railroad Avenue, and the route veers slightly to the left.

In the early 1950s, the State Road Department acquired part of the Kissimmee Valley Line of the Florida East Coast Railway in Orange and Seminole Counties for highway purposes.

One is located on Ryan Drive and Three Rivers Road in Carrabelle, connecting US 98 and CR 67 west of downtown.

The other is in Liberty County and bypasses Telogia to the northeast, shortening the distance between CR 67 and SR 65 south of Hosford.