The road runs through residential neighborhoods before crossing the Salem River into Mannington Township.

[1][2] Here, CR 540 turns to the east and forms a concurrency with Route 45, passing some homes before heading into farm fields with occasional residences.

From here, CR 540 heads southeast into more forested areas with occasional homes, entering Quinton Township.

Upon crossing the Maurice River in a forested area, the route continues east into Vineland in Cumberland County, where the name becomes Almond Road.

Past this intersection, CR 540 becomes a five-lane road with a center left-turn lane and enters commercial areas before passing homes.

From here, the road narrows back to two lanes and passes through wooded residential neighborhoods prior to reaching the CR 555 junction.